Ingestible Device for Medical Interaction with the Gastrointestinal Tract and Surrounding Tissues

Current gastrointestinal (GI) treatments often require costly, invasive procedures with limited accuracy. Traditional monitoring methods, such as endoscopies and surface electrogastrograms, are constrained by the physical limitations of external tools and epicutaneous measurements, which are prone to noise and lack spatial precision. There is a growing need for more specific, temporally precise, and less invasive approaches to improve diagnostic and therapeutic outcomes. Ingestible devices present a promising solution by providing direct access to the GI tract and enteric nervous system. These miniaturized, biocompatible capsules can monitor key physiological signals such as pH, temperature, pressure, and biomolecular activity while preserving natural GI function. Integrated multi-electrode systems allow for improved electrogastrogram recordings, tissue impedance testing, and neuromodulation of enteric and autonomic systems. These features position ingestible devices as a transformative tool for improving the precision, efficiency, and patient experience of GI care.