Brain to Brain Communication

Our Brain-to-Brain communication research focuses on advancing the precision of non-invasive recording and stimulation of the brain cortex. The precision is increased by the development of advanced optimization algorithms combined with accurate tissue modeling. The models are augmented by our development of hardware stimulation and recording systems to allow independent fine-tuned stimulation of large amount of channels and fast data transmission between multiple brain-interface devices in real-time. Our bold aim is to step beyond a brain-computer interface and instead make human brain to brain connection possible, thus making scientific fiction a reality.

 

Cross Frequency Coupling (CFC)

 

 

CFC-3

 

Cross Frequency Coupling (CFC) is the interaction between brain oscillations of different frequencies, and the coupling phenomenon has been observed in the brain of rodent and human. Phase-amplitude coupling (PAC) is a type of CFC, which describes the dependence between the phase of a low-frequency component and the amplitude of a high-frequency component of electrical brain activities. It has been claimed that the modulation of low frequency phase on high frequency amplitude plays a functional role in cognition and information processing, such as learning and memory. The change of PAC patterns has been associated with various neurological disorders, e.g., epilepsy and  schizophrenia.

Five seizure stages classified by firing patterns (on the left). PAC pattern comparisons between the conventional method (middle) and HHT method (right) of two patients.
Five seizure stages classified by firing patterns (on the left). PAC pattern comparisons between the conventional method (middle) and HHT method (right) of two patients.