Demonstration of Closed-loop Operation with Our Implantable Device

 

The blue and pink traces on the oscilloscope represents two of the many channels that are generating stimulation pulses, initially at 30Hz and 60Hz at different phase delays respectively. The green trace represents ADC recording that is wirelessly transmitted to a laptop running the closed-loop controller in real-time. Toggling the device’s analog recording sensor, the closed-loop controller on the laptop detects the change and modulates the stimulation protocols, communicating this back to the SoC chip wirelessly. The last portion of the video shows the new stimulation patterns of the blue and pink traces, at 30Hz and 20Hz, and phase delays respectively. In summary, we have demonstrated our system’s capability to simultaneously perform real-time recording and stimulation. Accordingly, it is feasible to implement closed-loop operations using our implantable system. A sophisticated controller is under development.

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The figure displays a demonstration of our closed-loop system performing real-time, multi-channel recording and stimulation. The green and yellow traces are EMG signals fed into the recording sensors of the chip. The information is transmitted wirelessly as input to a control algorithm that detects EMG envelopes over the chip’s multiple recording channels. The decision algorithm modulates the chips stimulation parameters to 60Hz (blue trace) and 20Hz (pink trace) when a large envelope is detected in the yellow EMG signal; and 20Hz (blue trace) and 30Hz (pink trace) when a large envelope is detected in the green EMG signal.